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Improved detection of pancreatic islets in vivo using double contrast

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F11%3A7116" target="_blank" >RIV/00216208:11130/11:7116 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023001:_____/11:00002468

  • Result on the web

    <a href="http://www.ncbi.nlm.nih.gov/pubmed/21861290" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21861290</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Improved detection of pancreatic islets in vivo using double contrast

  • Original language description

    The transplantation of pancreatic islets containing beta-cells, which produce insulin, is an alternative approach to the treatment of type 1 diabetes mellitus. The non-invasive visualization of transplanted islets can be performed using MRI; however, this requires labeling of the islets with a suitable contrast agent prior to transplantation. The detection of islets labeled by iron oxide-based contrast agents and transplanted into the liver tissue can be significantly improved using the intravenous administration of a suitable gadolinium contrast agent prior to MRI. The applied contrast agent not only improves the contrast-to-noise ratio, but also eliminates artifacts that may lead to an overestimation of the number of hypointense spots and their area;thus it improves the accuracy of automated and semi-automated procedures used for transplanted islet segmentation and quantification. Copyright (C) 2011 John Wiley & Sons, Ltd.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Contrast Media & Molecular Imaging

  • ISSN

    1555-4309

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    308-313

  • UT code for WoS article

    000295295100016

  • EID of the result in the Scopus database