Improved detection of pancreatic islets in vivo using double contrast
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F11%3A7116" target="_blank" >RIV/00216208:11130/11:7116 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/11:00002468
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/21861290" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21861290</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Improved detection of pancreatic islets in vivo using double contrast
Original language description
The transplantation of pancreatic islets containing beta-cells, which produce insulin, is an alternative approach to the treatment of type 1 diabetes mellitus. The non-invasive visualization of transplanted islets can be performed using MRI; however, this requires labeling of the islets with a suitable contrast agent prior to transplantation. The detection of islets labeled by iron oxide-based contrast agents and transplanted into the liver tissue can be significantly improved using the intravenous administration of a suitable gadolinium contrast agent prior to MRI. The applied contrast agent not only improves the contrast-to-noise ratio, but also eliminates artifacts that may lead to an overestimation of the number of hypointense spots and their area;thus it improves the accuracy of automated and semi-automated procedures used for transplanted islet segmentation and quantification. Copyright (C) 2011 John Wiley & Sons, Ltd.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Contrast Media & Molecular Imaging
ISSN
1555-4309
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
308-313
UT code for WoS article
000295295100016
EID of the result in the Scopus database
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