NMDA Receptors in Glial Cells: Pending Questions

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F13%3A10209754" target="_blank" >RIV/00216208:11130/13:10209754 - isvavai.cz</a>

Alternative codes found

RIV/68378041:_____/13:00395420

Result on the web

<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648778/" target="_blank" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648778/</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

NMDA Receptors in Glial Cells: Pending Questions

Original language description

Glutamate receptors of the N-methyl-D-aspartate (NMDA) type are involved in many cognitive processes, including behavior, learning and synaptic plasticity. For a long time NMDA receptors were thought to be the privileged domain of neurons; however, discoveries of the last 25 years have demonstrated their active role in glial cells as well. Despite the large number of studies in the field, there are many unresolved questions connected with NMDA receptors in glia that are still a matter of debate. The main objective of this review is to shed light on these controversies by summarizing results from all relevant works concerning astrocytes, oligodendrocytes and polydendrocytes (also known as NG2 glial cells) in experimental animals, further extended by studies performed on human glia. The results are divided according to the study approach to enable a better comparison of how findings obtained at the mRNA level correspond with protein expression or functionality. Furthermore, special atten

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Current Neuropharmacology

ISSN

1570-159X

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

3

Country of publishing house

AE - UNITED ARAB EMIRATES

Number of pages

13

Pages from-to

250-262

UT code for WoS article

000318152300002

EID of the result in the Scopus database

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