Cutaneous borreliosis associated with T cell-predominant infiltrates: A diagnostic challenge

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10295081" target="_blank" >RIV/00216208:11140/15:10295081 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jaad.2014.12.014" target="_blank" >http://dx.doi.org/10.1016/j.jaad.2014.12.014</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jaad.2014.12.014" target="_blank" >10.1016/j.jaad.2014.12.014</a>

Result language
angličtina
Original language name
Cutaneous borreliosis associated with T cell-predominant infiltrates: A diagnostic challenge
Original language description
Background: With the exception of erythema migrans, Borrelia infection of the skin manifests much more commonly with B cell-rich infiltrates. T cell-rich lesions have rarely been described. Objective: We report a series of 6 patients with cutaneous borreliosis presenting with T cell-predominant skin infiltrates. Methods: We studied the clinicopathologic and molecular features of 6 patients with T cell-rich skin infiltrates. Results: Half of the patients had erythematous patchy, partly annular lesions, and the other patients had features of acrodermatitis chronica atrophicans. Histopathology revealed a dense, band-like or diffuse dermal infiltrate. Apart from small, well differentiated lymphocytes, there were medium-sized lymphocytes with slight nuclearatypia and focal epidermotropism. An interstitial histiocytic component was found in 4 cases, including histiocytic pseudorosettes. Fibrosis was present in all cases but varied in severity and distribution. In 5 patients, borrelia DNA wa
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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