Evaluation of IL-2, IL-6, IL-8 and IL-10 in Malignant Melanoma Diagnostics
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10295859" target="_blank" >RIV/00216208:11140/15:10295859 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/15:10295859
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Evaluation of IL-2, IL-6, IL-8 and IL-10 in Malignant Melanoma Diagnostics
Original language description
Aim: The aim of the present study was to evaluate the usefulness of four interleukins (IL-2, IL-6, IL-8 and IL-10) for melanoma detection and correlate these interleukins with sentinel node metastasis positivity. Patients and Methods: A group of 236 persons was assessed: 175 patients with melanomas and 61 healthy persons. Melanoma patients were divided to four groups according to Breslow score. We determined IL-2, IL-6, IL-8 and IL-10 in each plasma sample. Interleukin plasma levels were assayed using aHuman Cytokine Milliplex Map kit. Measurements were performed using the Bio-Plex MAGPIX Multiplex Reader. Plasma samples were collected prior to surgery or any other form of treatment. All melanoma diagnoses were histologically verified. Results: We compared interleukin plasma levels in the healthy group and plasma levels in each Breslow score stage. In the first Breslow score stage, IL-2 (p< 0.0001), IL-6 (p= 0.0004) and IL-10 (p< 0.0001) were positive. In the second Breslow score, sta
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT11017" target="_blank" >NT11017: Serum and Tissue Markers as Prognostic factors in Malignant Melanoma</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Anticancer Research
ISSN
0250-7005
e-ISSN
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Volume of the periodical
35
Issue of the periodical within the volume
6
Country of publishing house
GR - GREECE
Number of pages
5
Pages from-to
3537-3541
UT code for WoS article
000355273800051
EID of the result in the Scopus database
2-s2.0-84931303930