Histology of abdominal incisions in rabbit - in vivo experiment with incorporation of artificial meshes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10298040" target="_blank" >RIV/00216208:11140/15:10298040 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Histology of abdominal incisions in rabbit - in vivo experiment with incorporation of artificial meshes

Original language description

Our aim was to analyze the tissue reaction to incorporation of artificial tissue-engineered mesh (PCL nanofibres) in rabbit after 6 weeks of regeneration. From histological point of view, the incision supported with scaffolds formed a more regularly arranged wound with more type I collagen than the incisions healing spontaneously without the scaffold support. The scaffolds were well integrated with the granular and dense connective tissue. The inflammatory cells found adjacent to the scaffolds formed nofoci weakening the wall. The scaffolds probably affected also formation of blood vessels in the adjacent region without incision, which resulted in a greater fraction of myofibroblasts in aminals with scaffolds when compared to animals without scaffolds.

Czech name

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Czech description

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Type

V_souhrn - Summary research report

CEP classification

EA - Morphology and cytology

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2015

Confidentiality

C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

Number of pages

16

Place of publication

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Publisher/client name

Technická univerzita v Liberci

Version

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