A new hitherto unreported histopathologic manifestation of mammary analogue secretory carcinoma: "masked MASC" associated with low-grade mucinous adenocarcinoma and low-grade in situ carcinoma components
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10327382" target="_blank" >RIV/00216208:11140/16:10327382 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1097/PAI.0000000000000320" target="_blank" >http://dx.doi.org/10.1097/PAI.0000000000000320</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/PAI.0000000000000320" target="_blank" >10.1097/PAI.0000000000000320</a>
Alternative languages
Result language
angličtina
Original language name
A new hitherto unreported histopathologic manifestation of mammary analogue secretory carcinoma: "masked MASC" associated with low-grade mucinous adenocarcinoma and low-grade in situ carcinoma components
Original language description
We present a salivary gland tumor of the parotid gland in a 54-year-old woman, which contained a minor mammary analogu secretory carcinoma (MASC) component (20%) intermixed with a morphologically entirely different mucinous adenocarcinomatous component that comprised 80% of the tumor mass and a morphologically nondescript low-grade intraductal carcinoma (in situ) component. On fluorescence in situ hybridization, a break in the ETV6 gene was documented in the mucinous adenocarcinomatous, the conventional MASC, and the intraductal (in situ) components. RT-PCR failed to reveal an ETV6-NTRK3 fusion. The entire conventional MASC and only rare mucinous adenocarcinoma tumor cells were mammaglobin positive, whereas the low-grade intraductal carcinoma (in-situ) component was negative. S-100 protein stained only the MASC component.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Immunohistochemistry and Molecular Morphology
ISSN
1541-2016
e-ISSN
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Volume of the periodical
24
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
"e80"-"e85"
UT code for WoS article
000386358600001
EID of the result in the Scopus database
2-s2.0-84955608092