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A new hitherto unreported histopathologic manifestation of mammary analogue secretory carcinoma: "masked MASC" associated with low-grade mucinous adenocarcinoma and low-grade in situ carcinoma components

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10327382" target="_blank" >RIV/00216208:11140/16:10327382 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1097/PAI.0000000000000320" target="_blank" >http://dx.doi.org/10.1097/PAI.0000000000000320</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1097/PAI.0000000000000320" target="_blank" >10.1097/PAI.0000000000000320</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A new hitherto unreported histopathologic manifestation of mammary analogue secretory carcinoma: "masked MASC" associated with low-grade mucinous adenocarcinoma and low-grade in situ carcinoma components

  • Original language description

    We present a salivary gland tumor of the parotid gland in a 54-year-old woman, which contained a minor mammary analogu secretory carcinoma (MASC) component (20%) intermixed with a morphologically entirely different mucinous adenocarcinomatous component that comprised 80% of the tumor mass and a morphologically nondescript low-grade intraductal carcinoma (in situ) component. On fluorescence in situ hybridization, a break in the ETV6 gene was documented in the mucinous adenocarcinomatous, the conventional MASC, and the intraductal (in situ) components. RT-PCR failed to reveal an ETV6-NTRK3 fusion. The entire conventional MASC and only rare mucinous adenocarcinoma tumor cells were mammaglobin positive, whereas the low-grade intraductal carcinoma (in-situ) component was negative. S-100 protein stained only the MASC component.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Applied Immunohistochemistry and Molecular Morphology

  • ISSN

    1541-2016

  • e-ISSN

  • Volume of the periodical

    24

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    "e80"-"e85"

  • UT code for WoS article

    000386358600001

  • EID of the result in the Scopus database

    2-s2.0-84955608092