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ČeštinaEnglish

Chemokines in tumor proximal fluids

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10337931" target="_blank" >RIV/00216208:11140/17:10337931 - isvavai.cz</a>

  • Result on the web

    <a href="http://biomed.papers.upol.cz/pdfs/bio/2017/01/05.pdf" target="_blank" >http://biomed.papers.upol.cz/pdfs/bio/2017/01/05.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2016.062" target="_blank" >10.5507/bp.2016.062</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Chemokines in tumor proximal fluids

  • Original language description

    Chemokines are chemotactic cytokines produced by leukocytes and other types of cells including tumor cells. Tumor cells also express functional chemokine receptors responding to chemokine signals, promoting cell survival, prolirferation and metastasis formation. Significant concentrations of chemokines are found in the tumor adjacent, non-vascular fluids, collectively called tumor proximal fluids. This review summarizes the expression of CC and CXC chemokines in these fluids. Increased chemokine levels are found in high-grade tumor proximal fluids rather than in low-grade tumors and benign conditions. The data confirm peritumoral fluid chemokines as sensitive diagnostic and prognostic markers, as well as offer support for chemokines and their receptors as potential targets for antitumor therapy.

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

    —

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    —

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Papers

  • ISSN

    1213-8118

  • e-ISSN

    —

  • Volume of the periodical

    161

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    9

  • Pages from-to

    41-49

  • UT code for WoS article

    000398093500006

  • EID of the result in the Scopus database

    2-s2.0-85016237722

Similar results(10)

Chemokine receptors in a regulation of interstitial lung fibrosis and inflammationChemokine receptors and their therapeutic opportunities in diseased lung: far beyond leukocyte traffickingThe expression of chemokine receptors on the human normal and pathological cells.