How phenotype guides management of the most common malignant salivary neoplasms of the larynx?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10338145" target="_blank" >RIV/00216208:11140/17:10338145 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s12325-017-0494-y" target="_blank" >http://dx.doi.org/10.1007/s12325-017-0494-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s12325-017-0494-y" target="_blank" >10.1007/s12325-017-0494-y</a>

Result language

angličtina

Original language name

How phenotype guides management of the most common malignant salivary neoplasms of the larynx?

Original language description

Salivary gland carcinomas of the larynx are uncommon. Adenoid cystic carcinoma is the most prevalent type of salivary gland carcinoma in this region, although other histologies such as mucoepidermoid carcinoma and adenocarcinomas have been reported. These tumors may present with advanced-stage due to nonspecific symptoms and their relatively slow-growing nature. The index of suspicion for a non-squamous cell carcinoma entity should be high when a submucosal mass is present. An accurate diagnosis is mandatory due to the impact each biologic entity has on treatment and outcome. Data concerning treatment and outcome are scarce, but primary surgery with utmost focus on free surgical margins is the treatment of choice. The role of adjuvant radiotherapy has not been well defined, although there is an agreement that it should be considered in advanced-stage or high-grade disease. This review considers only the most common malignant salivary neoplasms of the larynx with a focus on clinical management of these tumors.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30109 - Pathology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Advances in Therapy

ISSN

0741-238X

e-ISSN

—

Volume of the periodical

34

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

13

Pages from-to

813-825

UT code for WoS article

000398914200004

EID of the result in the Scopus database

2-s2.0-85013414388