Expression of programmed cell death protein 1 by tumor-infiltrating lymphocytes and tumor cells is associated with advanced tumor stage in patients with esophageal adenocarcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10362254" target="_blank" >RIV/00216208:11140/17:10362254 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/17:10362254
Result on the web
<a href="http://dx.doi.org/10.1245/s10434-017-5858-7" target="_blank" >http://dx.doi.org/10.1245/s10434-017-5858-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1245/s10434-017-5858-7" target="_blank" >10.1245/s10434-017-5858-7</a>
Alternative languages
Result language
angličtina
Original language name
Expression of programmed cell death protein 1 by tumor-infiltrating lymphocytes and tumor cells is associated with advanced tumor stage in patients with esophageal adenocarcinoma
Original language description
Despite recent advances in the therapy for adenocarcinoma of the esophagogastric junction (AEG), overall prognosis remains poor. Programmed cell death protein 1 (PD1) is a co-inhibitory receptor primarily expressed by T-cells. Tumor cells can escape anticancer immune responses by triggering the PD1 pathway. Moreover, PD1 receptor engagement on cancer cells may trigger tumor-intrinsic growth signals. This study aimed to evaluate the potential clinical relevance of PD1 expression by tumor-infiltrating lymphocytes (TILs) and cancer cells in the AEG.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Annals of Surgical Oncology
ISSN
1068-9265
e-ISSN
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Volume of the periodical
24
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
2698-2706
UT code for WoS article
000407040500036
EID of the result in the Scopus database
2-s2.0-85018493488