Neurotransplantation therapy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10376927" target="_blank" >RIV/00216208:11140/18:10376927 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/B978-0-444-64189-2.00025-1" target="_blank" >http://dx.doi.org/10.1016/B978-0-444-64189-2.00025-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-444-64189-2.00025-1" target="_blank" >10.1016/B978-0-444-64189-2.00025-1</a>

Result language
angličtina
Original language name
Neurotransplantation therapy
Original language description
Neurotransplantation may be a promising approach for therapy of cerebellar diseases characterized by a substantial loss of neurons. Neurotransplantation could rescue neurons from degeneration and maintain cerebellar reserve, facilitate cerebellar compensation, or help reconstruct damaged neural circuits by cell substitution. These mechanisms of action can be of varying importance according to the type of cerebellar disease. Neurotransplantation therapy in cerebellar ataxias is still at the stage of experimental studies. There is currently little knowledge regarding cerebellar patients. Nevertheless, data provided by experiments in animal models of cerebellar degeneration and both clinical studies and experiences in patients with other neurologic diseases enable us to suggest basic principles, expectations, limitations, and future directions of neurotransplantation therapy for cerebellar diseases.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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