Systematic COronary Risk Evaluation (SCORE) and 20-year risk of cardiovascular mortality and cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F20%3A10415104" target="_blank" >RIV/00216208:11140/20:10415104 - isvavai.cz</a>
Alternative codes found
RIV/00064190:_____/20:N0000049 RIV/00216208:11110/20:10415104
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=W7IHOfWBVH" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=W7IHOfWBVH</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ejim.2020.05.034" target="_blank" >10.1016/j.ejim.2020.05.034</a>
Alternative languages
Result language
angličtina
Original language name
Systematic COronary Risk Evaluation (SCORE) and 20-year risk of cardiovascular mortality and cancer
Original language description
Background: Cardiovascular disease (CVD) followed by cancer are the two leading causes of death worldwide. SCORE charts have been recommended in Europe to identify individuals at increased CVD risk. However, the SCORE ability to identify individuals at increased risk of cancer has not yet been evaluated. The aim of this study was to determine the SCORE chart calibration in a country with changing CVD epidemiology, and its discrimination ability to identify individuals at increased risk of cancer over 20-years. Methods: The present analysis includes data from two cross-sectional independent surveys within the Czech postMONICA study (randomly selected representative population samples of the Czech Republic, aged 25-64 years); 3209 individuals in 1997/98 and 3612 in 2006-2009. Results: The SCORE had reasonable discrimination to predict 10-year CVD mortality, but significantly overestimated the risk across all risk categories. During the 20-year follow up, high and very high-risk categories were associated with an increased risk of cancer morbidity (in particular colorectal, other gastrointestinal, lung and malignant skin) and cancer mortality, as compared to low risk category. Conclusions: The present study shows that periodical calibration testing of SCORE charts is needed in countries with changing CVD epidemiology. Furthermore, we show that in middle-aged individuals, identified by SCORE charts as being at high or very high risk for CVD, cancer morbidity and cancer mortality is increased. Rigorous cancer screening may be appropriate in this group, especially in countries with falling CVD mortality, where relative proportion of cancer mortality is increasing.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
<a href="/en/project/NV15-27109A" target="_blank" >NV15-27109A: Longitudinal trends in major cardiovascular risk factors and their predictive value in a population random sample, Czech post-MONICA study</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Internal Medicine
ISSN
0953-6205
e-ISSN
—
Volume of the periodical
79
Issue of the periodical within the volume
September
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
63-69
UT code for WoS article
000565775400012
EID of the result in the Scopus database
2-s2.0-85086167019