Activated protein C improves pial microcirculation in experimental endotoxemia in rats
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F12%3A10126972" target="_blank" >RIV/00216208:11150/12:10126972 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.mvr.2012.03.003" target="_blank" >http://dx.doi.org/10.1016/j.mvr.2012.03.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mvr.2012.03.003" target="_blank" >10.1016/j.mvr.2012.03.003</a>
Alternative languages
Result language
angličtina
Original language name
Activated protein C improves pial microcirculation in experimental endotoxemia in rats
Original language description
Introduction: The brain is one of the first organs affected clinically in sepsis. Microcirculatory alterations are suggested to be a critical component in the pathophysiology of sepsis. The aim of this study was to investigate the effects of recombinanthuman activated protein C (rhAPC) on the pial microcirculation in experimental endotoxemia using intravital microscopy. Our hypothesis is rhAPC protects pial microcirculation in endotoxemia.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microvascular Research
ISSN
0026-2862
e-ISSN
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Volume of the periodical
83
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
276-280
UT code for WoS article
000303690800003
EID of the result in the Scopus database
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