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Activated protein C improves pial microcirculation in experimental endotoxemia in rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F12%3A10126972" target="_blank" >RIV/00216208:11150/12:10126972 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.mvr.2012.03.003" target="_blank" >http://dx.doi.org/10.1016/j.mvr.2012.03.003</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.mvr.2012.03.003" target="_blank" >10.1016/j.mvr.2012.03.003</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Activated protein C improves pial microcirculation in experimental endotoxemia in rats

  • Original language description

    Introduction: The brain is one of the first organs affected clinically in sepsis. Microcirculatory alterations are suggested to be a critical component in the pathophysiology of sepsis. The aim of this study was to investigate the effects of recombinanthuman activated protein C (rhAPC) on the pial microcirculation in experimental endotoxemia using intravital microscopy. Our hypothesis is rhAPC protects pial microcirculation in endotoxemia.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Microvascular Research

  • ISSN

    0026-2862

  • e-ISSN

  • Volume of the periodical

    83

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    276-280

  • UT code for WoS article

    000303690800003

  • EID of the result in the Scopus database