Multispecies biofilm in an artificial wound bed-A novel model for in vitro assessment of solid antimicrobial dressings

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F14%3A10284030" target="_blank" >RIV/00216208:11150/14:10284030 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/14:43908522
Result on the web
<a href="http://dx.doi.org/10.1016/j.mimet.2014.05.008" target="_blank" >http://dx.doi.org/10.1016/j.mimet.2014.05.008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mimet.2014.05.008" target="_blank" >10.1016/j.mimet.2014.05.008</a>

Result language
angličtina
Original language name
Multispecies biofilm in an artificial wound bed-A novel model for in vitro assessment of solid antimicrobial dressings
Original language description
Wound infections represent a major problem, particularly in patients with chronic wounds. Bacteria in the wound exist mainly in the form of biofilms and are thus resistant to most antibiotics and antimicrobials. A simple and cost-effective in vitro modelof chronic wound biofilms applied for testing treatments and solid devices, especially wound dressings, is presented in this work. The method is based on the well-established Lubbock chronic wound biofilm transferred onto an artificial agar wound bed. The biofilm formed by four bacterial species (Staphylococcus aureus, Enterococcus faecalis, Bacillus subtilis and Pseudomonas aeruginosa) was stable for up to 48 h post-transplant. The applicability of the model was evaluated by testing two common iodinewound treatments. These observations indicate that this method enables assessing the effects of treatments on established resilient wound biofilms and is clinically highly relevant. (C) 2014 Elsevier B.V. All rights reserved.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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