Pregnancy in homozygous familial hypercholesterolemia - Importance of LDL-apheresis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10294646" target="_blank" >RIV/00216208:11150/15:10294646 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/15:10294646
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S1567568815000252" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1567568815000252</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.atherosclerosissup.2015.02.024" target="_blank" >10.1016/j.atherosclerosissup.2015.02.024</a>
Alternative languages
Result language
angličtina
Original language name
Pregnancy in homozygous familial hypercholesterolemia - Importance of LDL-apheresis
Original language description
Introduction: Rare cases of pregnancy in women with homozygous familial hypercholesterolemia (HFH) have been reported. HFH might pose significant risks for the mother and her fetus. Statins, the most potent agents for low-density lipoprotein (LDL) cholesterol reduction, are contraindicated; thus lipoprotein apheresis remains the only effective treatment. Case report: We report on a 34-year-old pregnant woman with HFH who was treated throughout the entire pregnancy by lipoprotein apheresis (immunoadsorption method). Increasing levels of LDL-cholesterol were stabilized at 9 e 10 mmol/L by lipoprotein apheresis (performed every 10 days). No complications were observed during the treatment procedures. Monitoring of the fetus revealed no impairment of the umbilical cord and blood flow in the uterine arteries, as well as no intrauterine growth retardation. The delivery was spontaneous and the child was breastfed for two months. Conclusion: Intensive treatment by lipoprotein apheresis is an e
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Atherosclerosis Supplements
ISSN
1567-5688
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
May
Country of publishing house
IE - IRELAND
Number of pages
6
Pages from-to
134-139
UT code for WoS article
000353796000021
EID of the result in the Scopus database
2-s2.0-84928893285