Enhanced Glutamine Availability Exerts Different Effects on Protein and Amino Acid Metabolism in Skeletal Muscle From Healthy and Septic Rats

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10296691" target="_blank" >RIV/00216208:11150/15:10296691 - isvavai.cz</a>

Alternative codes found

RIV/62690094:18450/15:50002555

Result on the web

<a href="http://pen.sagepub.com/content/39/7/847.full.pdf+html" target="_blank" >http://pen.sagepub.com/content/39/7/847.full.pdf+html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/0148607114537832" target="_blank" >10.1177/0148607114537832</a>

Result language

angličtina

Original language name

Enhanced Glutamine Availability Exerts Different Effects on Protein and Amino Acid Metabolism in Skeletal Muscle From Healthy and Septic Rats

Original language description

The aim of this study was to assess the effect of enhanced extracellular concentration of glutamine (GLN) on leucine oxidation, amino acid concentrations, and protein metabolism in skeletal muscle of intact, laparotomized, and septic rats. Cecal ligationand puncture was used as a model of sepsis. It is concluded that muscles with higher proportion of white fibers are more sensitive to septic stimuli than muscles with higher proportion of red fibers and that enhanced GLN availability exerts different effects on skeletal muscle in septic and healthy conditions. In sepsis may enhanced GLN availability correct GLN deficiency, inhibit BCAA catabolism and exert favorable effect on protein synthesis. In healthy state may enhanced GLN availability lead to severe alterations in intramuscular concentration of a number of amino acids and impair protein synthesis.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Parenteral and Enteral Nutrition

ISSN

0148-6071

e-ISSN

—

Volume of the periodical

39

Issue of the periodical within the volume

7

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

847-854

UT code for WoS article

000360413700012

EID of the result in the Scopus database

2-s2.0-84939635650