Glycocalyx in vivo measurement
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10369570" target="_blank" >RIV/00216208:11150/17:10369570 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/17:10369570 RIV/44555601:13450/17:43894532
Result on the web
<a href="http://dx.doi.org/10.3233/CH-179235" target="_blank" >http://dx.doi.org/10.3233/CH-179235</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3233/CH-179235" target="_blank" >10.3233/CH-179235</a>
Alternative languages
Result language
angličtina
Original language name
Glycocalyx in vivo measurement
Original language description
The endothelial glycocalyx (EG) lining the endoluminal surface of the capillaries has been proposed as a key component of the microcirculation and a major player in microvascular pathology. Recent advances in the understanding of its physiological role and clinical significance have been made upon the development of methods allowing EG assessment in clinical medicine. Laboratory methods can assess the amount of EG damage by measuring levels of its degradation products (e.g. syndecan-1, heparan sulphate and hyaluronan sulphate), mostly in the plasma, however, their physiological turnover disqualifies them from being the reliable index of EG damage. At the bedside, in vivo video microscopy tools technologies (e.g. Side-stream Dark Field imaging technology) allow indirect assessment of EG thickness in sublingual microcirculation by measuring the penetration extent (called Perfused Boundary Region) of flowing red blood cells into the EG.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
<a href="/en/project/NV15-31881A" target="_blank" >NV15-31881A: Alterations of glycocalyx in critical illness and during major surgery and approaches for glycocalyx protection</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Hemorheology and Microcirculation
ISSN
1386-0291
e-ISSN
—
Volume of the periodical
67
Issue of the periodical within the volume
3-4
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
5
Pages from-to
499-503
UT code for WoS article
000418073600033
EID of the result in the Scopus database
2-s2.0-85045410966