Endocan concentrations in postmortem serum, vitreous humor and urine in victims of lethal hypothermia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10370420" target="_blank" >RIV/00216208:11150/17:10370420 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/17:10370420

Result on the web

<a href="http://dx.doi.org/10.1016/j.jflm.2017.07.002" target="_blank" >http://dx.doi.org/10.1016/j.jflm.2017.07.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jflm.2017.07.002" target="_blank" >10.1016/j.jflm.2017.07.002</a>

Result language

angličtina

Original language name

Endocan concentrations in postmortem serum, vitreous humor and urine in victims of lethal hypothermia

Original language description

Endocan is a soluble molecule secreted from vascular endothelial cells of various organs. Its exact function in humans remains to be elucidated, though it has been postulated that increased tissue expression or serum levels of this molecule may be an indicator of endothelial activation and neovascularization. In the realm of forensic pathology, studies pertaining to endothelial activation following exposure to cold exclusively focused on thrombomodulin, a transmembrane protein specific to endothelial cells. In the study herein described, endocan concentrations were determined in postmortem serum, urine and vitreous humor samples collected during autopsy in a series of cases that underwent medicolegal investigations. A total of 76 autopsy cases were selected and three study groups (hypothermia group, sepsis group and non-hypothermia/non-sepsis group) prospectively formed during the study period. The obtained results seem to indicate that exposure to cold and subsequent death is not distinguished by significant endothelial dysfunction causing enhanced endocan secretion. (C) 2017 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30501 - Forensic science

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Forensic and Legal Medicine

ISSN

1752-928X

e-ISSN

—

Volume of the periodical

50

Issue of the periodical within the volume

August

Country of publishing house

GB - UNITED KINGDOM

Number of pages

5

Pages from-to

39-43

UT code for WoS article

000407721900007

EID of the result in the Scopus database

2-s2.0-85022051051