Enzyme stereospecificity as a powerful tool in searching for new enzymes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F10%3A00300581" target="_blank" >RIV/00216208:11160/10:00300581 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Enzyme stereospecificity as a powerful tool in searching for new enzymes

Original language description

Chirality is an important aspect of drug metabolism. Biotransformation of chiral and prochiral drugs is more complex because diverse formation of metabolite enantiomers. Drugs are often substrates for multiple enzymes and each can metabolize the drug with various stereospecifities. Differences in enzyme stereospecificity are possible to utilize in searching for new enzymes.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/GA303%2F07%2F0994" target="_blank" >GA303/07/0994: Targeting the novel human microsomal reductases causing resistance in cancer chemotherapy.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Current Drug Metabolism

ISSN

1389-2002

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

6

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

13

Pages from-to

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UT code for WoS article

000280130100007

EID of the result in the Scopus database

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