Photosynthesis-inhibiting effects of 2-benzylsulphanylbenzimidazoles in spinach chloroplasts

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F12%3A10124174" target="_blank" >RIV/00216208:11160/12:10124174 - isvavai.cz</a>

Result on the web

<a href="http://link.springer.com/content/pdf/10.2478%2Fs11696-012-0192-9" target="_blank" >http://link.springer.com/content/pdf/10.2478%2Fs11696-012-0192-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/s11696-012-0192-9" target="_blank" >10.2478/s11696-012-0192-9</a>

Result language

angličtina

Original language name

Photosynthesis-inhibiting effects of 2-benzylsulphanylbenzimidazoles in spinach chloroplasts

Original language description

Inhibition of photosynthetic electron transport (PET) in spinach chloroplasts by nineteen 2-benzylsulphanylbenzimidazoles (BZA) was studied. BZA were found to inhibit photosynthetic electron transport (PET) and for their inhibitory efficiency, electronicproperties of the R substituent on the benzyl moiety are decisive. The PET inhibiting activity of the studied BZA expressed as IC50 varied in the range from 28.5 mu M (R = 3,5-(CF3)(2)) to 394.5 mu M (R = 2,4-(NO2)(2)). For compounds with R = H, 4-CH3,3-CH3, 3-OCH3, 4-F, 3-F, 4-Cl, 3-Cl, 2-Cl, 4-Br, 3-Br, 3,4-F-2, 3,4-Cl-2, 3-CF3, 3,5-(CF3)(2) linear increase of the inhibitory activity with the increasing value of the substituent's sigma constant up to 0.86 was observed. Further increase of the sigmaconstant resulted in a sharp activity decrease of the corresponding compounds (R = 2-F-6-Cl, 2-NO2, 3,5-(NO2)(2), 2,4-(NO2)(2)). Using EPR spectroscopy and an artificial electron donor diphenyl carbazide it was found that the site of BZA

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemical Papers

ISSN

0366-6352

e-ISSN

—

Volume of the periodical

66

Issue of the periodical within the volume

8

Country of publishing house

SK - SLOVAKIA

Number of pages

5

Pages from-to

795-799

UT code for WoS article

000305460300011

EID of the result in the Scopus database

—