Stress relaxation study of fillers for directly compressed tablets
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F12%3A10124738" target="_blank" >RIV/00216208:11160/12:10124738 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0032591011006310" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0032591011006310</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.powtec.2011.11.011" target="_blank" >10.1016/j.powtec.2011.11.011</a>
Alternative languages
Result language
angličtina
Original language name
Stress relaxation study of fillers for directly compressed tablets
Original language description
It is possible to assess viscoelastic properties of materials by means of the stress relaxation test. This method records the decrease in pressing power in a tablet at its constant height. The cited method was used to evaluate the time-dependent deformation for six various materials: microcrystalline cellulose, cellulose powder, hydroxypropyl methylcellulose, mannitol, lactose monohydrate. and hydrogen phosphate monohydrate. The decrease in pressing powering of a tablet during a 180s period was described mathematically by the parameters of three exponential equations, where the whole course of the stress relaxation is divided into three individual processes (instant elastic deformation, retarded elastic deformation and permanent plastic deformation). Three values of the moduli of plasticity and elasticity were calculated for each compound. The values of elastic parameters A(Ti) have a strong relationship with bulk density. The plastic parameters P-Ti represent particle tendency to form
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Powder Technology
ISSN
0032-5910
e-ISSN
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Volume of the periodical
217
Issue of the periodical within the volume
1
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
6
Pages from-to
510-515
UT code for WoS article
000301159500067
EID of the result in the Scopus database
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