Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F13%3A10144248" target="_blank" >RIV/00216208:11160/13:10144248 - isvavai.cz</a>

Result on the web

<a href="http://www.ptfarm.pl/pub/File/Acta_Poloniae/2013/1/129-135.pdf" target="_blank" >http://www.ptfarm.pl/pub/File/Acta_Poloniae/2013/1/129-135.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses

Original language description

The paper compared two spray-dried lactoses Flowlac (R) 100 and SuperTab (R) 14SD from the standpoint of tensile strength and disintegration time of tablets, the effect of an addition of the lubricant magnesium stearate and silicified microcrystalline cellulose on these properties, and also from the standpoint of the energy profile of compression. The comparison of the values was performed at the compression force of 15 IN. The strength of tablets was higher in the case of SuperTab 14SD, an increase inthe concentration of magnesium stearate did not decrease tablet strength. Prosolv SMCC 90 increased the strength of tablets and made it equal for both lactoses, but it also increased the sensitivity to the added lubricant. The disintegration time of tablets was shorter in the case of SuperTab 14SD, an increased concentration of magnesium stearate prolonged it, and an addition of Prosolv SMCC 90 shortened it and made it equal for both lactoses. From the energy standpoint, the maximal ener

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Poloniae Pharmaceutica

ISSN

0001-6837

e-ISSN

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Volume of the periodical

70

Issue of the periodical within the volume

1

Country of publishing house

PL - POLAND

Number of pages

7

Pages from-to

129-135

UT code for WoS article

000316432000015

EID of the result in the Scopus database

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