Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F16%3A10327781" target="_blank" >RIV/00216208:11160/16:10327781 - isvavai.cz</a>
Result on the web
<a href="http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1557902" target="_blank" >http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1557902</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/s-0035-1557902" target="_blank" >10.1055/s-0035-1557902</a>

Result language
angličtina
Original language name
Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway
Original language description
Flavonoids are important components of human diet and they have been claimed to possess a significant antiplatelet potential. 29 mainly natural flavonoids were tested for their antiplatelet effects on the arachidonic acid cascade. The isoflavonoids genistein and daidzein were shown to possess both marked cyclooxygenase-1 inhibitory activity and acted also as antagonists on thromboxane receptors. In conclusion, the consumption of few flavonoids in a diet, particularly of the isoflavonoids genistein and daidzein, may positively influence platelet aggregation.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
<a href="/en/project/GBP303%2F12%2FG163" target="_blank" >GBP303/12/G163: Centre of drug-dietary supplements interactions and nutrigenetics</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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