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A UHPLC method for the rapid separation and quantification of anthocyanins in acai berry and dry blueberry extracts

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F17%3A10362176" target="_blank" >RIV/00216208:11160/17:10362176 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S0731708517309421" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0731708517309421</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jpba.2017.05.045" target="_blank" >10.1016/j.jpba.2017.05.045</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A UHPLC method for the rapid separation and quantification of anthocyanins in acai berry and dry blueberry extracts

  • Original language description

    The presented work describes the development and validation of a rapid UHPLC-UV method using a core-shell particle column with a pentafluorophenyl stationary phase for the separation and quantitative analysis of the six anthocyanins in acai berry and dry blueberry extracts. The anthocyanins (cyanidin-3-glucoside, cyanidin-3-rutenoside, delphinidin-3-galactoside, delphinidin-3-glucoside, delphinidin-3-rutenoside, and peonidin-3-glucoside) were separated and analyzed in 5 min. The chromatographic separation was performed on a Kinetex PFP (150 x 2.1 mm) core-shell column with a particle size of 1.7 mu m at a temperature of 50 degrees C. Acetonitrile was used as mobile phase B and 5% formic acid, filtrated through a 0.22 mu m filter, as mobile phase A. They were delivered at a flow rate of 0.55 mL min(-1) according to the elution gradient program. The detection wavelength was set at 520 nm. A solid-liquid extraction with a solution of methanol and a 5% water solution of formic acid (25+75 v/v) using an ultrasonic bath was chosen for the preparation of the available commercial samples of food supplements with a content of acai berry extract and blueberry extract. Under optimal chromatographic conditions, the method was validated. Recoveries for all analyzed anthocyanins were 97.8-102.6% and the relative standard deviation ranged from 0.4% to 3.0% for within-day and from 0.6% to 3.1% for between-day repeatability. The limits of detection were in the range of 0.11-0.14 mu g mL(-1).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30104 - Pharmacology and pharmacy

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Pharmaceutical and Biomedical Analysis

  • ISSN

    0731-7085

  • e-ISSN

  • Volume of the periodical

    143

  • Issue of the periodical within the volume

    September

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    10

  • Pages from-to

    204-213

  • UT code for WoS article

    000405537300027

  • EID of the result in the Scopus database

    2-s2.0-85020667534