Recent developments in supercritical fluid chromatography - mass spectrometry: Is it a viable option for analysis of complex samples?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F19%3A10400890" target="_blank" >RIV/00216208:11160/19:10400890 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=LbsDo5sucB" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=LbsDo5sucB</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.trac.2018.12.023" target="_blank" >10.1016/j.trac.2018.12.023</a>
Alternative languages
Result language
angličtina
Original language name
Recent developments in supercritical fluid chromatography - mass spectrometry: Is it a viable option for analysis of complex samples?
Original language description
Supercritical fluid chromatography (SFC) is known since the early 1960's and it has gone through several ups and downs during the past 50 years. The most remarkable rebirth came at the beginning of the millennium, when SFC gained its popularity in many laboratories due to the significant improvements in instrumentation resulting in high reliability and robustness. New developments in SFC column chemistries and possibility of mixing CO2 with organic solvents allowed the analysis of various compounds differing in polarities, acid-base properties, and molecular weight. Hyphenation of advanced SFC platforms with mass spectrometry (MS) provides benefits similar to liquid chromatography (LC) hyphenated with MS, i.e. sensitivity and selectivity. SFC is complementary to the most widely used reversed phase LC due to the similar polarity profile to normal phase LC. This orthogonality and different separation mechanism can effectively solve the presence of matrix effects or challenging separations. In addition, SFC can be beneficial in analysis of chiral or unstable compounds difficult to analyze in LC or GC. Current SFC-MS is mostly used as a fast and green approach in a variety of research fields including bioanalysis, omics sciences, plant, food, and environmental analyses.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/EF15_003%2F0000465" target="_blank" >EF15_003/0000465: Establishment of Specialized Team for Advanced Research on Separation Science</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Trends in Analytical Chemistry
ISSN
0165-9936
e-ISSN
—
Volume of the periodical
112
Issue of the periodical within the volume
March
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
14
Pages from-to
212-225
UT code for WoS article
000458499300017
EID of the result in the Scopus database
2-s2.0-85060306462