[2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with alpha,omega-Diynes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10062362" target="_blank" >RIV/00216208:11310/10:10062362 - isvavai.cz</a>

Alternative codes found

RIV/61388963:_____/10:00356369

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

[2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with alpha,omega-Diynes

Original language description

6-Alkynyl-7-benzylpurines were prepared by the Sonogashira reaction from 6-chloro-7-benzylpurines and terminal alkynes. The prepared alkynylpurines were cyclotrimerized with various 1,6-diynes in the presence of Ni(cod)2/2PPh3 catalytic system into the corresponding 6-aryl-7-benzylpurines under ambient conditions. The prepared 6-alkynyl- and 6-aryl-7-benzylpurines were tested for cytostatic activity

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

<a href="/en/project/1M0508" target="_blank" >1M0508: New Antivirals and Antineoplastics</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Heterocycles

ISSN

0385-5414

e-ISSN

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Volume of the periodical

82

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

13

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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