Stress-induced pseudocyst formation - A newly identified mechanism of protection against organic solvents in Acanthamoeba of the T4 genotype

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10099500" target="_blank" >RIV/00216208:11310/11:10099500 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.protis.2010.03.006" target="_blank" >http://dx.doi.org/10.1016/j.protis.2010.03.006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.protis.2010.03.006" target="_blank" >10.1016/j.protis.2010.03.006</a>

Result language

angličtina

Original language name

Stress-induced pseudocyst formation - A newly identified mechanism of protection against organic solvents in Acanthamoeba of the T4 genotype

Original language description

Differentiation into highly resistant double-walled cysts is a major mechanism allowing amphizoic acanthamoebae to survive under long-lasting, unfavourable environmental conditions. We found that relatively low concentrations of methanol, acetone or DMSOstimulate prompt Acanthamoeba differentiation into a rounded cyst-like stage with a single envelope. To address whether this rapid response differs from the encystment, time-dependent changes in cell surface characteristics and cyst-specific gene expression were monitored in encystating cells and cells differentiating under methanol treatment using microscopic, lectin-binding, PCR and resistance studies.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Protist

ISSN

1434-4610

e-ISSN

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Volume of the periodical

162

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

12

Pages from-to

58-69

UT code for WoS article

000285628800005

EID of the result in the Scopus database

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