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Determination of benzocaine using HPLC and FIA with amperometric detection on a carbon paste electrode

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10104905" target="_blank" >RIV/00216208:11310/11:10104905 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1002/elan.201000646" target="_blank" >http://dx.doi.org/10.1002/elan.201000646</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/elan.201000646" target="_blank" >10.1002/elan.201000646</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determination of benzocaine using HPLC and FIA with amperometric detection on a carbon paste electrode

  • Original language description

    A new method for benzocaine determination employing FIA and HPLC with electrochemical detection on a carbon paste electrode was developed. The optimum conditions for the determination were found. Carrier solution for FIA consisted of B-R buffer pH 4 (80%methanol, v/v) and used flow rate was 1.0 mLmin(-1). Mobile phase for HPLC consisted of B-R buffer pH 4 (75% methanol, v/v) with flow rate 0.4 mLmin(-1). Working potential of +1.2 V was employed. Practical applicability of the methods was tested on thedetermination of benzocaine in selected pharmaceuticals. The results were in agreement with results obtained using spectrophotometric detection and with one exception also with the content declared by the manufacturer.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LC06035" target="_blank" >LC06035: Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Electroanalysis

  • ISSN

    1040-0397

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    5

  • Pages from-to

    662-666

  • UT code for WoS article

    000288093400014

  • EID of the result in the Scopus database