GFP-like Fluorophores as DNA Labels for Studying DNA-Protein Interactions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10126881" target="_blank" >RIV/00216208:11310/12:10126881 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/12:00382270 RIV/61388963:_____/12:00382270
Result on the web
<a href="http://dx.doi.org/10.1021/jo301684b" target="_blank" >http://dx.doi.org/10.1021/jo301684b</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jo301684b" target="_blank" >10.1021/jo301684b</a>

Result language
angličtina
Original language name
GFP-like Fluorophores as DNA Labels for Studying DNA-Protein Interactions
Original language description
The design of four new fluorinated biaryl fluorescent labels and their attachment to nucleosides and nucleoside triphosphates (dNTPs) by the aqueous cross-coupling reactions of biarylboronates is reported. The modified dNTPs were good substrates for KODXL polymerase and were enzymatically incorporated into DNA probes. The photophysical properties of the biaryl-modified nucleosides, dNTPs, and DNA were studied systematically. Some labels were used for detection of secondary structure changes, mismatch pairing or pH microenvironment.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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