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Efficient high-throughput sequencing of a laser microdissected chromosome arm

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10189110" target="_blank" >RIV/00216208:11310/13:10189110 - isvavai.cz</a>

  • Alternative codes found

    RIV/00027162:_____/13:#0001029

  • Result on the web

    <a href="http://dx.doi.org/10.1186/1471-2164-14-357" target="_blank" >http://dx.doi.org/10.1186/1471-2164-14-357</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/1471-2164-14-357" target="_blank" >10.1186/1471-2164-14-357</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Efficient high-throughput sequencing of a laser microdissected chromosome arm

  • Original language description

    Background: Genomic sequence assemblies are key tools for a broad range of gene function and evolutionary studies. The diploid amphibian Xenopus tropicalis plays a pivotal role in these fields due to its combination of experimental flexibility, diploid genome, and early-branching tetrapod taxonomic position, having diverged from the amniote lineage similar to 360 million years ago. A genome assembly and a genetic linkage map have recently been made available. Unfortunately, large gaps in the linkage mapattenuate long-range integrity of the genome assembly. Results: We laser dissected the short arm of X. tropicalis chromosome 7 for next generation sequencing and computational mapping to the reference genome. This arm is of particular interest as it encodes the sex determination locus, but its genetic map contains large gaps which undermine available genome assemblies. Whole genome amplification of 15 laser-microdissected 7p arms followed by next generation sequencing yielded similar to

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GPP502%2F11%2FP522" target="_blank" >GPP502/11/P522: Physical mapping of Xenopus tropicalis genome.</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BMC Genomics

  • ISSN

    1471-2164

  • e-ISSN

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    May 2013

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

  • UT code for WoS article

    000321385600001

  • EID of the result in the Scopus database