The in vivo J-difference editing MEGA-PRESS technique for the detection of n-3 fatty acids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F14%3A10287036" target="_blank" >RIV/00216208:11310/14:10287036 - isvavai.cz</a>

Alternative codes found

RIV/00023001:_____/14:00059101

Result on the web

<a href="http://dx.doi.org/10.1002/nbm.3189" target="_blank" >http://dx.doi.org/10.1002/nbm.3189</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/nbm.3189" target="_blank" >10.1002/nbm.3189</a>

Result language

angličtina

Original language name

The in vivo J-difference editing MEGA-PRESS technique for the detection of n-3 fatty acids

Original language description

In this study, we present a method for the detection of n-3 fatty acid (n-3 FA) signals using MRS in adipose tissue in vivo. This method (called oMEGA-PRESS) is based on the selective detection of the CH3 signal of n-3 FA using the MEGA-PRESS (MEshcher-GArwood Point-RESolved Spectroscopy) J-difference editing technique. We optimized the envelope shape and frequency of spectral editing pulses to minimize the spurious co-editing and incomplete subtraction of the CH3 signal of other FAs, which normally obscure the n-3 FA CH3 signal in MR spectra acquired using standard PRESS techniques. The post-processing of the individual data scans with the phase and frequency correction before data subtraction and averaging was implemented to further improve the quality of in vivo spectra. The technique was optimized in vitro on lipid phantoms using various concentrations of n-3 FA and examined in vivo at 3 T on 15 healthy volunteers. The proportion of n-3 FA estimated by the oMEGA-PRESS method in pha

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

<a href="/en/project/GPP208%2F11%2FP059" target="_blank" >GPP208/11/P059: New techniques of in-vivo MR spectroscopy for the study of adipose tissue triglycerides</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

NMR in Biomedicine

ISSN

0952-3480

e-ISSN

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Volume of the periodical

27

Issue of the periodical within the volume

11

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

1293-1299

UT code for WoS article

000343927900004

EID of the result in the Scopus database

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