Equivalent peak resolution: Characterization of the extent of separation for two components based on their relative peak overlap

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10294250" target="_blank" >RIV/00216208:11310/15:10294250 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/elps.201400475" target="_blank" >http://dx.doi.org/10.1002/elps.201400475</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elps.201400475" target="_blank" >10.1002/elps.201400475</a>

Result language

angličtina

Original language name

Equivalent peak resolution: Characterization of the extent of separation for two components based on their relative peak overlap

Original language description

Although the classical formula of peak resolution was derived to characterize the extent of separation only for Gaussian peaks of equal areas, it is often used even when the peaks follow non-Gaussian distributions and/or have unequal areas. This practicecan result in misleading information about the extent of separation in terms of the severity of peak overlap. We propose here the use of the equivalent peak resolution value, a term based on relative peak overlap, to characterize the extent of separation that had been achieved. The definition of equivalent peak resolution is not constrained either by the form(s) of the concentration distribution function(s) of the peaks (Gaussian or non-Gaussian) or the relative area of the peaks. The equivalent peak resolution value and the classically defined peak resolution value are numerically identical when the separated peaks are Gaussian and have identical areas and SDs. Using our new freeware program, Resolution Analyzer, one can calculate bot

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Electrophoresis

ISSN

0173-0835

e-ISSN

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Volume of the periodical

36

Issue of the periodical within the volume

5

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

646-654

UT code for WoS article

000350547400004

EID of the result in the Scopus database

2-s2.0-84923768573