Intracellular microRNA profiles form in the Xenopus laevis oocyte that may contribute to asymmetric cell division
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10314054" target="_blank" >RIV/00216208:11310/15:10314054 - isvavai.cz</a>
Alternative codes found
RIV/86652036:_____/15:00446657
Result on the web
<a href="http://dx.doi.org/10.1038/srep11157" target="_blank" >http://dx.doi.org/10.1038/srep11157</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/srep11157" target="_blank" >10.1038/srep11157</a>
Alternative languages
Result language
angličtina
Original language name
Intracellular microRNA profiles form in the Xenopus laevis oocyte that may contribute to asymmetric cell division
Original language description
Asymmetric distribution of fate determinants within cells is an essential biological strategy to prepare them for asymmetric division. In this work we measure the ntracellular distribution of 12 maternal microRNAs (miRNA) along the animal-vegetal axis ofthe Xenopus laevis oocyte using qPCR tomography. We find the miRNAs have distinct intracellular profiles that resemble two out of the three profiles we previously observed for mRNAs. Our results suggest that miRNAs in addition to proteins and mRNAs mayhave asymmetric distribution within the oocyte and may contribute to asymmetric cell division as cell fate determinants.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0109" target="_blank" >ED1.1.00/02.0109: Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
JUN 10 2015
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
1-9
UT code for WoS article
000356086400001
EID of the result in the Scopus database
2-s2.0-84931292254