Mouse polyomavirus: Propagation, purification, quantification, and storage

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10320535" target="_blank" >RIV/00216208:11310/15:10320535 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/9780471729259.mc14f01s38" target="_blank" >http://dx.doi.org/10.1002/9780471729259.mc14f01s38</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/9780471729259.mc14f01s38" target="_blank" >10.1002/9780471729259.mc14f01s38</a>

Result language

angličtina

Original language name

Mouse polyomavirus: Propagation, purification, quantification, and storage

Original language description

Mouse polyomavirus (MPyV) is a member of the Polyomaviridae family, which comprises non-enveloped tumorigenic viruses infecting various vertebrates including humans and causing different pathogenic responses in the infected organisms. Despite the variations in host tropism and pathogenicity, the structure of the virions of these viruses is similar. The capsid, with icosahedral symmetry (o, 45 nm, T= 7d), is composed of a shell of 72 capsomeres of structural proteins, arranged around the nucleocore containing approximately 5-kbp-long circular dsDNA in complex with cellular histones. MPyV has been one of the most studied polyomaviruses and serves as a model virus for studies of the mechanisms of cell transformation and virus trafficking, and for use in nanotechnology. It can be propagated in primary mouse cells (e.g., in whole mouse embryo cells) or in mouse epithelial or fibroblast cell lines. In this unit, propagation, purification, quantification, and storage of MPyV virions are prese

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/GA13-26115S" target="_blank" >GA13-26115S: Delivery of Polyomavirus genomes into the cell nucleus and interactions of their structural proteins in host cells</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Current Protocols in Microbiology

ISSN

1934-8525

e-ISSN

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Volume of the periodical

2015

Issue of the periodical within the volume

neuveden

Country of publishing house

US - UNITED STATES

Number of pages

26

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-84949234034