Chromatographic Characterization of a New Cationic beta-CD Based Stationary Phase Prepared by Dynamic Coating
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F16%3A10323993" target="_blank" >RIV/00216208:11310/16:10323993 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s10337-016-3050-z" target="_blank" >http://dx.doi.org/10.1007/s10337-016-3050-z</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10337-016-3050-z" target="_blank" >10.1007/s10337-016-3050-z</a>
Alternative languages
Result language
angličtina
Original language name
Chromatographic Characterization of a New Cationic beta-CD Based Stationary Phase Prepared by Dynamic Coating
Original language description
Cyclodextrin-based stationary phases are frequently used for separation of various isomers. The main reason for applying new cyclodextrin (CD) derivatives for HPLC stationary phases is the improvement of separation efficiency. This paper introduces a new stationary phase prepared by dynamic coating of ion-exchanger with a newly synthesized cationic derivative of beta-cyclodextrin. This mono-substituted derivative of beta-cyclodextrin contains two tetraalkylammonium groups in its side chain. Diverse sets of analytes were tested to reveal the separation potential of the derivatized stationary phase. This dynamically coated stationary phase exhibited mostly better selectivity and resolution than a commercial chemically bonded beta-cyclodextrin stationary phase. Mixtures of analytes were baseline resolved in shorter analysis time. Furthermore, interactions participating in the retention mechanism were identified using a linear free energy relationship approach and ionic interaction study. Lower hydrophobicity and higher ability to interact as hydrogen bond donor affect retention on the coated stationary phase. Even though the ionic interaction study confirmed that the surface of the ion-exchanger was modified by dynamic coating, the ionic interactions still contributed to the retention mechanism on the coated stationary phase.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chromatographia
ISSN
0009-5893
e-ISSN
—
Volume of the periodical
79
Issue of the periodical within the volume
9-10
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
529-536
UT code for WoS article
000376125000001
EID of the result in the Scopus database
2-s2.0-84962689049