Synthesis and radical scavenging activity of cinnamic acid esters

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F17%3A10367839" target="_blank" >RIV/00216208:11310/17:10367839 - isvavai.cz</a>

Result on the web

<a href="http://bcc.bas.bg/BCC_Volumes/Volume_49_Special_E_2017/BCC-49-E-2017-68-73-Chochkova-14.pdf" target="_blank" >http://bcc.bas.bg/BCC_Volumes/Volume_49_Special_E_2017/BCC-49-E-2017-68-73-Chochkova-14.pdf</a>

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Synthesis and radical scavenging activity of cinnamic acid esters

Original language description

Cinnamic and hydoxycinnamic acid esters (alpha, beta-unsaturated esters), functional derivatives of cinnamic acids (cinnamic, ferulic, sinapic, caffeic) are secondary plant methabolites derived from phenylpropanoid pathway. Cinnamates, of both natural and synthetic origin, continue to elicit great interest due to diversity of biological activities they possess, such as: antioxidant, antimicrobial, anticancer, anti-inflammatory, anti-tyrosinase and etc. Herein, the reduction of N alpha- and side chain protected amino acids to N-protected amino alcohols and the coupling of the latest with hydroxycinnamic (sinapic and ferulic) acids is described. 1,1-Diphenyl-2-picrylhydrazyl (DPPH radical) scavenging activities of hydroxycinnamates were compared with their corresponding N-hydroxycinnamoyl amino acid amides. Free hydroxycinnamic acids were used as positive controls. The results indicated that N-hydroxycinnamoyl amino acid amides exhibited lower scavenging ability than the corresponding free hydroxycinnamic acids, but higher one than hydroxycinnamates.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10608 - Biochemistry and molecular biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bulgarian Chemical Communications

ISSN

0324-1130

e-ISSN

—

Volume of the periodical

49

Issue of the periodical within the volume

Special Issue E

Country of publishing house

BG - BULGARIA

Number of pages

6

Pages from-to

68-73

UT code for WoS article

000418303600015

EID of the result in the Scopus database

—