Chiral Nafion membranes prepared by strong electrostatic binding of multiply positively charged beta-cyclodextrin derivatives for tryptophan racemic mixtures' separation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F21%3A10430801" target="_blank" >RIV/00216208:11310/21:10430801 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11320/21:10430801
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=adkDH1wQvZ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=adkDH1wQvZ</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mtcomm.2021.102234" target="_blank" >10.1016/j.mtcomm.2021.102234</a>
Alternative languages
Result language
angličtina
Original language name
Chiral Nafion membranes prepared by strong electrostatic binding of multiply positively charged beta-cyclodextrin derivatives for tryptophan racemic mixtures' separation
Original language description
Three multiply positively charged beta-cyclodextrin derivatives were prepared and ionically bound to a Nafion (R) 117 membrane. The derivatives differed only in the length of the linker, which connects the positively charged anchor to the cyclodextrin moiety. The resulting membranes exert preferential sorption of L-enantiomer of tryptophan from its racemic mixture (ee reaching 44 % for the medium linker length). The membrane follows the retarded transport mechanism. Using a fluorophore-tagged cyclodextrin modifier, we confirmed no leaching of the modifier from the membrane. Thus, we proved the potential of the approach of electrostatic binding of chiral selectors for the enantioseparation of chiral drugs.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
<a href="/en/project/FV10082" target="_blank" >FV10082: Novel stationary phases for chromatographic separation of chiral compounds</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Materials Today Communications [online]
ISSN
2352-4928
e-ISSN
—
Volume of the periodical
27
Issue of the periodical within the volume
June
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
102234
UT code for WoS article
000683034600005
EID of the result in the Scopus database
2-s2.0-85102622535