Chiral Nafion membranes prepared by strong electrostatic binding of multiply positively charged β-cyclodextrin derivatives for tryptophan racemic mixtures’ separation.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F21%3A00541140" target="_blank" >RIV/67985858:_____/21:00541140 - isvavai.cz</a>
Result on the web
<a href="http://hdl.handle.net/11104/0318741" target="_blank" >http://hdl.handle.net/11104/0318741</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mtcomm.2021.102234" target="_blank" >10.1016/j.mtcomm.2021.102234</a>
Alternative languages
Result language
angličtina
Original language name
Chiral Nafion membranes prepared by strong electrostatic binding of multiply positively charged β-cyclodextrin derivatives for tryptophan racemic mixtures’ separation.
Original language description
Three multiply positively charged β-cyclodextrin derivatives were prepared and ionically bound to a Nafion® 117 membrane. The derivatives differed only in the length of the linker, which connects the positively charged anchor to the cyclodextrin moiety. The resulting membranes exert preferential sorption of l-enantiomer of tryptophan from its racemic mixture (ee reaching 44 % for the medium linker length). The membrane follows the retarded transport mechanism. Using a fluorophore-tagged cyclodextrin modifier, we confirmed no leaching of the modifier from the membrane. Thus, we proved the potential of the approach of electrostatic binding of chiral selectors for the enantioseparation of chiral drugs.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20402 - Chemical process engineering
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Materials Today Communications
ISSN
2352-4928
e-ISSN
2352-4928
Volume of the periodical
27
Issue of the periodical within the volume
JUN 2021
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
102234
UT code for WoS article
000683034600005
EID of the result in the Scopus database
2-s2.0-85102622535