Enantioselective Organocatalytic Synthesis of 1,2,3-Trisubstituted Cyclopentanes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F21%3A10432595" target="_blank" >RIV/00216208:11310/21:10432595 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=I-x4fWY._s" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=I-x4fWY._s</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ejoc.202100841" target="_blank" >10.1002/ejoc.202100841</a>

Result language
angličtina
Original language name
Enantioselective Organocatalytic Synthesis of 1,2,3-Trisubstituted Cyclopentanes
Original language description
An organocatalytic asymmetric domino Michael/alpha-alkylation reaction between enals and non-stabilized alkyl halides has been developed. Chiral secondary amine catalyzed cyclization reaction of 1-bromo-3-nitropropane with alpha,beta-unsaturated aldehydes provides 1,2,3-trisubstituted cyclopentane carbaldehydes with high diastereo- (dr up to 8 : 1) and enantioselectivities (ee up to 96 %).
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10401 - Organic chemistry

Project
<a href="/en/project/GA20-29336S" target="_blank" >GA20-29336S: Enantioselective transformations using Brønsted acid catalysis and aminocatalysis (BACA)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)