All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Sphingolipid levels crucially modulate lateral microdomain organization of plasma membrane in living yeast

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F14%3A10283120" target="_blank" >RIV/00216208:11320/14:10283120 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/14:00430431

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.febslet.2013.11.038" target="_blank" >http://dx.doi.org/10.1016/j.febslet.2013.11.038</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.febslet.2013.11.038" target="_blank" >10.1016/j.febslet.2013.11.038</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sphingolipid levels crucially modulate lateral microdomain organization of plasma membrane in living yeast

  • Original language description

    We report sphingolipid-related reorganization of gel-like microdomains in the plasma membrane of living Saccharomyces cerevisiae using trans-Parinaric acid (t-PnA) and 1,6-diphenyl-1,3,5-hexatriene (DPH). Compared to control, the gel-like domains were significantly reduced in the membrane of a sphingolipid-deficient lcb1-100 mutant. The same reduction resulted from sphingolipid depletion by myriocin. The phenotype could be reverted when a myriocin-induced block in sphingolipid biosynthesis was bypassedby exogenous dihydrosphingosine. Lipid order of less-ordered membrane regions decreased with sphingolipid depletion as well, as documented by DPH fluorescence anisotropy. The data indicate that organization of lateral microdomains is an essential physiological role of these structural lipids. (C) 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP205%2F12%2F0720" target="_blank" >GAP205/12/0720: Role of membrane potential in the lateral microdomain organization of the plasma membrane</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    FEBS Letters

  • ISSN

    0014-5793

  • e-ISSN

  • Volume of the periodical

    588

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    443-449

  • UT code for WoS article

    000329976800010

  • EID of the result in the Scopus database