Low-carbohydrate diet among children with type 1 diabetes: A multi-center study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F21%3A10433550" target="_blank" >RIV/00216208:11320/21:10433550 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/21:43922494 RIV/65269705:_____/21:00075832 RIV/00064203:_____/21:10433550 RIV/00216208:11130/21:10433550 RIV/00064173:_____/21:N0000244
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=PFa1r07dtV" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=PFa1r07dtV</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/nu13113903" target="_blank" >10.3390/nu13113903</a>
Alternative languages
Result language
angličtina
Original language name
Low-carbohydrate diet among children with type 1 diabetes: A multi-center study
Original language description
Aims/hypothesis: The proportion of children with type 1 diabetes (T1D) who have experience with low-carbohydrate diet (LCD) is unknown. Our goal was to map the frequency of LCD among children with T1D and to describe their clinical and laboratory data. Methods: Caregivers of 1040 children with T1D from three centers were addressed with a structured questionnaire regarding the children's carbohydrate intake and experience with LCD (daily energy intake from carbohydrates below 26% of age-recommended values). The subjects currently on LCD were compared to a group of non-LCD respondents matched to age, T1D duration, sex, type and center of treatment. Results: A total of 624/1040 (60%) of the subjects completed the survey. A total of 242/624 (39%) subjects reported experience with voluntary carbohydrate restriction with 36/624 (5.8%) subjects currently following the LCD. The LCD group had similar HbA1c (45 vs. 49.5, p = 0.11), lower average glycemia (7.0 vs. 7.9, p = 0.02), higher time in range (74 vs. 67%, p = 0.02), lower time in hyperglycemia >10 mmol/L (17 vs. 20%, p = 0.04), tendency to more time in hypoglycemia <3.9 mmol/L(8 vs. 5%, p = 0.05) and lower systolic blood pressure percentile (43 vs. 74, p = 0.03). The groups did not differ in their lipid profile nor in current body height, weight or BMI. The LCD was mostly initiated by the parents or the subjects themselves and only 39% of the families consulted their decision with the diabetologist. Conclusions/interpretation: Low carbohydrate diet is not scarce in children with T1D and is associated with modestly better disease control. At the same time, caution should be applied as it showed a tendency toward more frequent hypoglycemia.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
<a href="/en/project/NU21-01-00085" target="_blank" >NU21-01-00085: Low-carbohydrate diet in type 1 diabetes: effects on glycemic control and islet autoimmunity</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nutrients [online]
ISSN
2072-6643
e-ISSN
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Volume of the periodical
13
Issue of the periodical within the volume
11
Country of publishing house
CH - SWITZERLAND
Number of pages
12
Pages from-to
3903
UT code for WoS article
000725170000001
EID of the result in the Scopus database
2-s2.0-85118098726