Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F01%3A00004871" target="_blank" >RIV/00216224:14110/01:00004871 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion
Original language description
The extracellular matrix (ECM) provides signalling cues that regulate cell behaviour during peripheral nerve formation and homeostasis. Composition of the ECM is the major determinant of the microenvironmental condition that controls the nerve regeneration. To reveal different microenvironmental conditions for motor and afferent axons we have analysed immunohistochemically some ECM components and adhesion molecules (laminin-2, -3, fibronectin, thrombospondin, tenascin, chondroitin sulphate, and HNK-1) in the spinal roots and branches of the spinal nerve. The results of quantitative immunofluorescence analysis suggest some differences in the content of ECM along the afferent and motor axons that could be involved in the origin of different conditions for the axon regrowth after injury of the dorsal and ventral roots as well as the spinal nerves.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA309%2F00%2F0407" target="_blank" >GA309/00/0407: Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2001
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The Histochemical Journal
ISSN
0018-2214
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
4
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
2
Pages from-to
247
UT code for WoS article
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EID of the result in the Scopus database
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