Immunohistochemical and immunogold analysis of laminins in the peripheral nerve structures

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F01%3A00004875" target="_blank" >RIV/00216224:14110/01:00004875 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Immunohistochemical and immunogold analysis of laminins in the peripheral nerve structures

Original language description

The basal laminae of the peripheral nervous system are produced by Schwann and perineurial cells. Laminins, predominant glycoproteins of the basal laminae, play a role in adherence, growth, morphology, migration, and differentiation of the cells. There is conclusive evidence that laminin molecules promote the axon outgrowth and migration of Schwann cells. Laminins are heterotrimers composed of a,b and g chains that combine to form at least 11 isoforms. It is assumed that different compartments of the peripheral nervous system exhibit different laminin isoforms. Therefore, we have localised a distribution of laminin-1, -2, and -3 isoforms and some individual laminin chains (a1,b2,b3,g2) in the rat femoral nerve and Pacinian corpuscles by indirect immunofluorescence technique. In addition, location of laminin-1,-2, and -3 isoforms were studied in Pacinian corpuscles by immunogold electron microscopic technique. The results of immunohistochemical and immunogold detection of laminins confi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/GA309%2F00%2F0407" target="_blank" >GA309/00/0407: Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The Histochemical Journal

ISSN

0018-2214

e-ISSN

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Volume of the periodical

33

Issue of the periodical within the volume

4

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

2

Pages from-to

233

UT code for WoS article

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EID of the result in the Scopus database

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