IMMUNOHISTOCHEMICAL AND IMMUNOGOLD ANALYSIS OF LAMININS IN THE PERIPHERAL NERVE STRUCTURES
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F00%3A00003130" target="_blank" >RIV/00216224:14110/00:00003130 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
IMMUNOHISTOCHEMICAL AND IMMUNOGOLD ANALYSIS OF LAMININS IN THE PERIPHERAL NERVE STRUCTURES
Original language description
The endoneurium and perineurium of femoral nerve displayed immunofluorescence for laminin-1, -2, and -3 isoforms. A granular immunostaining was observed in the endoneurium and perineurium when antibodies against a1 and b2 laminin chains were used. Immunostaining for b3 and g2 laminin chains revealed distinct fluorescence in the Schwann cells, while the perineurium expressed predominantly punctate immunofluorescence. The inner core of Pacinian corpuscles derived from specialized Schwann cells displayed immunofluorescence staining for laminin-1, -2, and -3 as well as for individual laminin chains (a1, b2, b3, g2). In addition, antibodies against a1 and b2 laminin chains provided a weak fluorescence in the axon terminals and superficial layers of the capsule. The results indicate that Schwann cells and their derived structures exhibit not only laminin-1, -2, -3 isoforms but also laminin-5 suggested from immunohistochemical identification of g2 chain.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA309%2F00%2F0407" target="_blank" >GA309/00/0407: Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2000
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
37th Proceeding of Czech Society of Histochemistry and Cytochemistry
ISBN
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ISSN
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e-ISSN
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Number of pages
1
Pages from-to
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Publisher name
MU Brno
Place of publication
Brno
Event location
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Event date
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Type of event by nationality
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UT code for WoS article
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