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Bilateral quantitative changes of laminin-1 in the spinal nerve roots after unilateral sciatic nerve injury

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00042873" target="_blank" >RIV/00216224:14110/09:00042873 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Bilateral quantitative changes of laminin-1 in the spinal nerve roots after unilateral sciatic nerve injury

  • Original language description

    Changes of laminin-1 (lam-1) were investigated in rat spinal nerve roots after unilateral sciatic nerve ligature. Spinal nerve roots of naive rats displayed lam-1 immunostaining in the basal laminae on outer surface of Schwann cell/axon units with higherbrightness in ventral than dorsal roots. Bilateral enhancement of lam-1 immunofluorescence was found in the endoneurium of roots 1 and 3 days after nerve ligature. Compared to rats surviving for 1 or 3 days, apparent bilateral decrease of lam-1 immunofluorescence brightness was observed in both roots 7 days after nerve injury. The lam-1 alterations in ipsi- and contralateral roots were similar, but more distinct in roots of ipsilateral side. The results suggest that quantitative changes of lam-1 are present bilaterally in the endoneurium of spinal nerve roots after unilateral sciatic nerve ligature.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    9th European Meeting on Glial Cells in Health and Disease

  • ISBN

    978-88-7587-520-6

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

  • Publisher name

    Medimond S.r.l.

  • Place of publication

    Bologna (Italy)

  • Event location

    Paris (France)

  • Event date

    Sep 8, 2009

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    ISI:00027007550