Bilateral quantitative changes of laminin-1 in the spinal nerve roots after unilateral sciatic nerve injury
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00042873" target="_blank" >RIV/00216224:14110/09:00042873 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Bilateral quantitative changes of laminin-1 in the spinal nerve roots after unilateral sciatic nerve injury
Original language description
Changes of laminin-1 (lam-1) were investigated in rat spinal nerve roots after unilateral sciatic nerve ligature. Spinal nerve roots of naive rats displayed lam-1 immunostaining in the basal laminae on outer surface of Schwann cell/axon units with higherbrightness in ventral than dorsal roots. Bilateral enhancement of lam-1 immunofluorescence was found in the endoneurium of roots 1 and 3 days after nerve ligature. Compared to rats surviving for 1 or 3 days, apparent bilateral decrease of lam-1 immunofluorescence brightness was observed in both roots 7 days after nerve injury. The lam-1 alterations in ipsi- and contralateral roots were similar, but more distinct in roots of ipsilateral side. The results suggest that quantitative changes of lam-1 are present bilaterally in the endoneurium of spinal nerve roots after unilateral sciatic nerve ligature.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
9th European Meeting on Glial Cells in Health and Disease
ISBN
978-88-7587-520-6
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
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Publisher name
Medimond S.r.l.
Place of publication
Bologna (Italy)
Event location
Paris (France)
Event date
Sep 8, 2009
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
ISI:00027007550