Mechanical Restitution in Left and Right Guinea Pig Ventricular Preparations

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F02%3A00006315" target="_blank" >RIV/00216224:14110/02:00006315 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Mechanical Restitution in Left and Right Guinea Pig Ventricular Preparations

Original language description

The study was focused on identification of possible differences in the onset and time course of mechanical restitution in guinea pig multicellular heart preparations, i.e., papillary muscles from the right and left ventricles. Stimulated twitches of bothpreparations mounted in a horizontal perfusion bath were recorded simultaneously. Mechanical restitution curves were constructed at 25C and 35C and at stimulation rates of 0.5 Hz, 1 Hz and 2 Hz. No statistically significant differences in restitution curves of both preparations were found. It can be concluded that, in the assessment of mechanical behaviour of the heart, the guinea pig left ventricular papillary muscle appears to be a suitable substitute for the conventionally employed right ventricularpapillary muscles.

Czech name

Mechanical Restitution in Left and Right Guinea Pig Ventricular Preparations

Czech description

The study was focused on identification of possible differences in the onset and time course of mechanical restitution in guinea pig multicellular heart preparations, i.e., papillary muscles from the right and left ventricles. Stimulated twitches of bothpreparations mounted in a horizontal perfusion bath were recorded simultaneously. Mechanical restitution curves were constructed at 25C and 35C and at stimulation rates of 0.5 Hz, 1 Hz and 2 Hz. No statistically significant differences in restitution curves of both preparations were found. It can be concluded that, in the assessment of mechanical behaviour of the heart, the guinea pig left ventricular papillary muscle appears to be a suitable substitute for the conventionally employed right ventricularpapillary muscles.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

<a href="/en/project/GA102%2F01%2F1494" target="_blank" >GA102/01/1494: Optical recording of action potentials and its application in cardiology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scripta medica

ISSN

1211-3395

e-ISSN

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Volume of the periodical

75

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

187

UT code for WoS article

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EID of the result in the Scopus database

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