Changes in the cytoskeleton of P19 cells during apoptosis associated with induced differentiation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F02%3A00006512" target="_blank" >RIV/00216224:14110/02:00006512 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Changes in the cytoskeleton of P19 cells during apoptosis associated with induced differentiation
Original language description
The aim of the work was to study the morphology of microtubules and actin filaments during the apoptosis accompanying the differentiation of P19 cells. Mesodermal differentiation was induced by dimtehylsulfoxide and retinoic acid was used for induction of neuronal differentiation. To summarize, actin cytoskeleton actively participates in the executive phase of apoptosis whereas microtubules are only passively degraded in consequence of tubulin proteolysis.
Czech name
Changes in the cytoskeleton of P19 cells during apoptosis associated with induced differentiation
Czech description
The aim of the work was to study the morphology of microtubules and actin filaments during the apoptosis accompanying the differentiation of P19 cells. Mesodermal differentiation was induced by dimtehylsulfoxide and retinoic acid was used for induction of neuronal differentiation. To summarize, actin cytoskeleton actively participates in the executive phase of apoptosis whereas microtubules are only passively degraded in consequence of tubulin proteolysis.

Project
<a href="/en/project/GA304%2F00%2F0403" target="_blank" >GA304/00/0403: Changes of the cytoskeleton in tumour cell lines during induced apoptosis in relation to different stages of differentiation</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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