Interaction of cannabinoid methanandamide with processes of sensitization to both behavioral and immunological methamphetamine effects in mice.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F04%3A00010248" target="_blank" >RIV/00216224:14110/04:00010248 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Interaction of cannabinoid methanandamide with processes of sensitization to both behavioral and immunological methamphetamine effects in mice.
Original language description
The phenomenon of sensitization enhancing usually stimulant behavioral response to repeatedly administered drugs of abuse has been described both in laboratory animals and human beings. There is also data available confirming a cross-sensitization between different types of drugs of abuse supporting further the hypothesis that repeated use of one drug of abuse may facilitate the consumption of other drugs. Previously we confirmed the sensitization to methamphetamine (MET) stimulatory effect on locomotor/exploratory behavior, and also to its inhibitory influence on aggression in mice. Furthermore, such sensitization was present in mice cross-sensitized with cannabinoid methanandamide (CAN). Our experiences with behavioral as well as immunological profiles of different cannabinoids received in our collaborative studies with Israel colleagues (Mechoulam R., Fride E.) gave rise to the present study comparing cross-sensitization with CAN to behavioral MET effects with their influences on im
Czech name
Interakce kanabinoidu metanandamidu s procesy sensitizace k behaviorálním a imunologickým účinklům metamfetaminu u myší
Czech description
Byly potvrzeny funkční interakce mezi endokanabinboidním systémem a farmakologickými mechanismy metamfetaminu v obou studovaných parametrech.
Classification
Type
D - Article in proceedings
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Abstracts - NIDA International Forum 2004, San Juan, Puerto Rico
ISBN
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ISSN
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e-ISSN
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Number of pages
1
Pages from-to
90
Publisher name
US National Institute on Drug Abuse
Place of publication
USA
Event location
San Juan, Puerto Rico
Event date
Jan 1, 2004
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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