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A heterogeneous immunofluorescence staining for laminin-1 and related basal lamina molecules in the dorsal root ganglia following constriction nerve injury

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F05%3A00012985" target="_blank" >RIV/00216224:14110/05:00012985 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A heterogeneous immunofluorescence staining for laminin-1 and related basal lamina molecules in the dorsal root ganglia following constriction nerve injury

  • Original language description

    The bodies of primary sensory neurons and their satellite glial cells (SGCs) are limited by the basal laminae from extracellular matrix of the dorsal rot ganglia (DRG). The basal laminae displayed uniform immunofluorescence staining for laminin-1 in thesections of rat intact (naive) DRG. A proximal or distal ligature of the spinal nerves resulted in a heterogeneous immunostaining for laminin-1 around neuron-SGC units in the sections of corresponding DRG. The pattern of irregular laminin-1 immunofluorescence was more extensive in the ipsilateral than contralateral DRG of the operated rats. The immunofluorescence for laminin-1 exactly coincided with binding of Concanavalin-A as well as immunostaining for type IV collagen in both naive DRG and DRG affected by nerve ligature. Nidogen immunostaining decreased or fully disappeared at the surface of SGCs consistently with immunofluorescence staining for laminin-1, but retained or increased in the endothelial cells and ED-1 positive cells inv

  • Czech name

    Heterogenní immunofluorescenční lokalizace lamininu-1 a souvísejících molekul lamina basalis ve spinálních gangliích potkana po konstrikci nervu

  • Czech description

    Heterogenní immunofluorescenční lokalizace lamininu-1 a souvísejících molekul lamina basalis ve spinálních gangliích potkana po konstrikci nervu

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA309%2F03%2F1199" target="_blank" >GA309/03/1199: Changes of the satellite glial cells and their extracellular matrix after axotomy - conditions for the sympathetic sprouts in the spinal ganglia?</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Histochem Cell Biol

  • ISSN

    0948-6143

  • e-ISSN

  • Volume of the periodical

    125

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    671-680

  • UT code for WoS article

  • EID of the result in the Scopus database