Matrix metalloproteinase-2 promoter variability in psoriasis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00038937" target="_blank" >RIV/00216224:14110/09:00038937 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Matrix metalloproteinase-2 promoter variability in psoriasis

Original language description

A significant association of GG genotype of -790 MMP-2 polymorphism with psoriasis was observed (Pcorr=0,04). MMP-2 located in the psoriasis susceptibility region on 16q (psoriasis susceptibility 8, PSORS8) should be considered as a gene modulator of psoriasis in specific subgroups of patients. In the future, similar genetic characteristics could contribute to the data assembly of genetic predisposition to psoriasis and could lead to therapy improvement based on time-proved individual pharmacogenetic aspects detected in psoriasis patients.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FO - Dermatology and venereology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Archives of Dermatological Research

ISSN

0340-3696

e-ISSN

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Volume of the periodical

301

Issue of the periodical within the volume

6

Country of publishing house

DE - GERMANY

Number of pages

7

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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