All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Genotype association of C(-735)T polymorphism in matrix metalloproteinase 2 gene with G(8002)A endothelin 1 gene with plaque psoriasis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F02%3A00006175" target="_blank" >RIV/00216224:14110/02:00006175 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/02:00028026

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    Genotype association of C(-735)T polymorphism in matrix metalloproteinase 2 gene with G(8002)A endothelin 1 gene with plaque psoriasis

  • Original language description

    Excessive angiogenesis is one of the characteristic features of psoriasis. To determine the possible genetic background of neo-angiogenesis in plaque psoriasis, frequent polymorphisms in matrix metalloproteinase 2 (MMP-2) and endothelin 1 (ET-1) genes were studied. A significant difference in genotype distribution of C(-735)T MMP-2 between psoriatic and control patients was found (pcorr=0.008). Two associated genotypes (CCGG and CTGG) of the two polymorphisms were significantly less frequent in psoriatic patients (pcorr=0.03 and pcorr=0.008, respectively). The results seem to reflect a different susceptibility of MMP-2 as well as of some associated MMP-2 and ET-1 genotypes to psoriasis.

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

    —

Result continuities

  • Project

    <a href="/en/project/VS96097" target="_blank" >VS96097: Molecular pathophysiology of selected multigenic related to civilization diseases</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2002

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Dermatology

  • ISSN

    1018-8665

  • e-ISSN

    —

  • Volume of the periodical

    204

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    4

  • Pages from-to

    262

  • UT code for WoS article

    —

  • EID of the result in the Scopus database

    —

Similar results(10)

Three Retionoid X Receptor Gene Polymorphisms in Plaque Psoriasis and Psoriasis GuttataMatrix metalloproteinase-2 promoter variability in psoriasisAssociation of gelatinase a (MMP-2) and endothelin-1 gene polymorphism with plaque psoriasis.